Key word: HT-29, HT29, Growth curve, subcutaneous, Efficacy, immune system humanized, PBMC, T cell, NK, EGFR, 4-1BB, PD-1, 5FU
1、Growth curve
Case 1：
Inoculation method: subcutaneous.
2、Growth curve in systematic PBMC humanized mice model
Case1:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: first generation(PBMC).
Case2:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: first generation(PBMC).
Case3:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: first generation(PBMC).
Case4:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: first generation(PBMC)??.
Case5:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: second-generation(iHuPBMC-NK).
3、Growth curve in Tumor-PBMC-Mixed (s.c.) mice model
No Data
4、Growth curve in CD34+ HSC mice model
No Data
5、Growth curve with efficacy(?)
Case1:
Inoculation method: subcutaneous;
SOC: 5-FU;
Drug type: Chemotherapy.
6、Growth curve in systematic PBMC humanized mice model with efficacy(?)
Case1:
Inoculation method: subcutaneous;
Systematic PBMC humanized type: second-generation(iHuPBMC-T);
Target genes: EGFR, 4-1BB, PD-1;
SOC: Bi-ab(EGFR×4-1BB), PD-1;
Drug type: immunotherapy (immune checkpoint inhibitor).
7、Growth curve in Tumor-PBMC-Mixed (s.c.) mice model with efficacy(?)
No Data
8、Growth curve in CD34+ HSC mice model with efficacy(?)
No Data
about InnoModels Biotechnology (Beijing) Co., Ltd：InnoModels Biotech (Beijing) Co., Ltd. was founded by scientists from Novo Nordisk China R&D Center, Sino American Coronavirus, and Shanghai Jiao Tong University Institute of Immunology.InnoModels Biotech has domestic stability of the humanized mice immune system model (ihs) platform, and anthropogenic tumor allografts platform (symbol), focusing on tumor and tumor immune pharmacodynamics CRO services, translational medicine research service, individualized medicine, service transformation of new drug research and development enterprise, medical researchers, cancer patients, is dedicated to the research and development of tumor and tumor immunotherapy to provide close to the clinical trials of a new generation of animal models.
Web：www.imodels.tech
Web：http://en.imodels.tech
source：http://en.imodels.tech/blank211.html?introId=242
