《感染性疾病与免疫（英文）》2025年第1期已在本刊官网上线！本期主要内容有：述评类文章“麻风：一个从未消失的疾病”；指南共识类文章“中国艾滋病诊疗指南（2024版）”；论著类文章“COVID-19患者入院首日给予恢复期血浆的有效性：一项非盲随机对照试验”、“一例罕见ST353型猪链球菌导致严重眼内炎伴双侧耳聋的基因组特征研究”；综述类文章“老年HIV感染者的免疫衰老及其相关合并症”、“HBV/HIV合并感染：流行病学、发病机制和治疗”、“儿童慢性乙型肝炎的流行病学、自然病史和转归”；此外，本期还报道了“中国广东省1例长期糖尿病患者感染Francisella novicida后死亡”的病例报告和“如何从实体组织中提取单细胞悬液用于单细胞转录组学研究”的研究方案等精彩内容。读者可扫描文章二维码查看原文，或点击文章下方“阅读原文”前往官网阅读。
Contents
·Editorial
Leprosy: a disease that has never gone away
Qing Zhao, Hong Liu, Furen Zhang
通信作者：张福仁
引用本文：Zhao Q, Liu H, Zhang F. Leprosy: a disease that has never gone away. Infect Dis Immun 2025;5(1):1–3. doi:10.1097/ID9.0000000000000132
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·Consensus and Guideline
Chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition)
Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention
通信作者：李太生
引用本文：Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese center for disease control and prevention. chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition). Infect Dis Immun 2025;5(1):4–27. doi:10.1097/ID9.0000000000000152
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·Original Articles
The effectiveness of convalescent plasma administered on the first day of admission for COVID-19 patients: an open-label randomized controlled trial
Saeed Mohammadi, Mandana Pouladzadeh, Hamidreza Kouhpayeh, Shamsi Okati, Mehdi Safdarian, Peyman Eshghi, Parastoo Moradi Choghakabodi, Shahabeddin Mashaei, Sharareh Sanei Sistani, Yalda Khani, Soheila Nasizadeh, Ahmad Reza Shamshiri, Amir Teimourpour
通信作者：Peyman Eshghi
引用本文：Mohammadi S, Pouladzadeh M, Kouhpayeh H, et al. The effectiveness of convalescent plasma administered on the first day of admission for COVID-19 patients: an open-label randomized controlled trial. Infect Dis Immun 2025;5(1):28–35. doi:10.1097/ID9.0000000000000145
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Genomic characteristics of aStreptococcus suisof ST353 resulting in severe endophthalmitis with bilateral deafness
Liang Shen, Yanfei Tong, Shichao Li, Yuda Chen, Ruhan A, Zhen Li, Wenling Wang, Lijuan Yin, Jiuming Zou, Ziyong Sun, Changcheng Wu, Wenjie Tan
通信作者：谭文杰、吴长城、孙自镛
引用本文：Shen L, Tong Y, Li S, et al. Genomic characteristics of a Streptococcus suis of ST353 resulting in severe endophthalmitis with bilateral deafness. Infect Dis Immun 2025;5(1):36–43. doi:10.1097/ID9.0000000000000146
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·Review
Immunosenescence and its related comorbidities in older people living with HIV
【综述】粟斌教授及合作团队 | 老年HIV感染者的免疫衰老及其相关合并症
Xiao-Yan He, Xiu-Wen Wang, Shuang Li, Na Li, Wei Li, Yan Hu, Na Guo, Yong-Tang Zheng, Hong-Yi Zheng, Bin Su
通信作者：粟斌、郑宏毅、郑永唐
引用本文：He XY, Wang XW, Li S, et al. Immunosenescence and its related comorbidities in older people living with HIV. Infect Dis Immun 2025;5(1):44–55. doi:10.1097/ID9.0000000000000134
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Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment
Yaozu He, Weiyin Lin, Fei Gu, Xianglong Lan, Linghua Li
通信作者：李凌华
引用本文：He Y, Lin W, Gu F, et al. Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment. Infect Dis Immun 2025;5(1):56–61. doi:10.1097/ID9.0000000000000123
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Epidemiology, natural history, and outcome of chronic hepatitis B in children
Chenyang Huang, Jing Li, Min Zhang, Junliang Fu, Fu-Sheng Wang
通信作者：王福生
引用本文：Huang C, Li J, Zhang M, et al. Epidemiology, natural history, and outcome of chronic hepatitis B in children. Infect Dis Immun 2025;5(1):62–67. doi:10.1097/ID9.0000000000000130
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·Case Report
A patient with long-term diabetes dies following infection withFrancisella novicidain Guangdong province, China: a case report
Linjin Fan, Jialong Guan, Lizhi Feng, Yulong Wang, Huimin Zeng, Ying Zhu, Hao Li, Qiang Chen, Linghua Li, Jun Qian, Linna Liu, Yueping Li
通信作者：钱军、刘林娜、李粤平
引用本文：Fan L, Guan J, Feng L, et al. A patient with long-term diabetes dies following infection with Francisella novicida in Guangdong province, China: a case report. Infect Dis Immun 2025;5(1):68–71. doi:10.1097/ID9.0000000000000147
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·Study Protocol
Think twice: how single-cell suspensions from solid tissues for single-cell transcriptomics are well prepared
Meng-Meng Qu, Yan-Mei Jiao
通信作者：焦艳梅
引用本文：Qu MM, Jiao YM. Think twice: how single-cell suspensions from solid tissues for single-cell transcriptomics are well prepared. Infect Dis Immun 2025;5(1):72–74. doi:10.1097/ID9.0000000000000136
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